{"id":134767,"date":"2024-10-19T07:44:59","date_gmt":"2024-10-19T07:44:59","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/astm-e1242\/"},"modified":"2024-10-24T23:53:59","modified_gmt":"2024-10-24T23:53:59","slug":"astm-e1242","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/astm\/astm-e1242\/","title":{"rendered":"ASTM-E1242"},"content":{"rendered":"

ASTM E1242-97-Reapproved2014<\/h3>\n

Historical Standard: Standard Practice for Using Octanol-Water Partition Coefficient to Estimate Median Lethal Concentrations for Fish Due to Narcosis<\/h4>\n
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ASTM E1242<\/h4>\n

Scope<\/strong><\/p>\n

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1.1<\/span> This practice covers a procedure for estimating the fathead minnow (Pimephales promelas<\/span>) 96-h LC50 of nonreactive (that is, covalently bonded without unsaturated residues) and nonelectrolytic (that is, require vigorous reagents to facilitate substitution, addition, replacement reactions and are non-ionic, non-dissociating in aqueous solutions) organic chemicals acting solely by narcosis, also referred to as Meyer-Overton toxicity relationship.2<\/span><\/span><\/p>\n<\/p><\/div>\n

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1.2<\/span> This procedure is accurate for organic chemicals that are toxic due to narcosis and are non-reactive and non-electrolytic. Examples of appropriate chemicals are: alcohols, ketones, ethers, simple halogenated aliphatics, aromatics, and aliphatic substituted aromatics. It is not appropriate for chemicals whose structures include a potential toxiphore (that structural component of a chemical molecule that has been identified to show mammalian toxicity, for example CN is known to be reponsible for inactivation of enzymes, NO2<\/span><\/sub> for decoupling of oxidative phosphorylation, both leading to mammalian toxicity). Examples of inappropriate chemicals are: carbamates, organophosphates, phenols, beta-gamma unsaturated alcohols, electrophiles, and quaternary ammonium salts.<\/p>\n<\/p><\/div>\n

Keywords<\/strong><\/p>\n

ICS Code<\/strong><\/p>\n

ICS Number Code 07.080 (Biology. Botany. Zoology)<\/p>\n

DOI:<\/strong> 10.1520\/E1242-97R14<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

E1242-97(2014) Standard Practice for Using Octanol-Water Partition Coefficient to Estimate Median Lethal Concentrations for Fish Due to Narcosis<\/b><\/p>\n\n\n\n\n
Published By<\/td>\nPublication Date<\/td>\nNumber of Pages<\/td>\n<\/tr>\n
ASTM<\/b><\/a><\/td>\n2014<\/td>\n2<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"featured_media":134770,"template":"","meta":{"rank_math_lock_modified_date":false,"ep_exclude_from_search":false},"product_cat":[2637],"product_tag":[],"class_list":{"0":"post-134767","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-astm","8":"first","9":"instock","10":"sold-individually","11":"shipping-taxable","12":"purchasable","13":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product\/134767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media\/134770"}],"wp:attachment":[{"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/media?parent=134767"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_cat?post=134767"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/pdfstandards.shop\/wp-json\/wp\/v2\/product_tag?post=134767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}